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当前位置: 首页 > 产品中心 > Flow_cytometry > U-CyTech/mAb抗小鼠IL-2(克隆S4B6-1)/0.5mg/CT336
商品详细U-CyTech/mAb抗小鼠IL-2(克隆S4B6-1)/0.5mg/CT336
U-CyTech/mAb抗小鼠IL-2(克隆S4B6-1)/0.5mg/CT336
U-CyTech/mAb抗小鼠IL-2(克隆S4B6-1)/0.5mg/CT336
商品编号: CT336
品牌: ucytech
市场价: ¥4640.00
美元价: 2784.00
产地: 美国(厂家直采)
公司:
产品分类: 流式抗体
公司分类: Flow_cytometry
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Catalogue Number
CT336
Description
mAb anti-mouse IL-2 (clone S4B6-1) - 0.5 mg
Price
€232.00
Characteristics
clone S4B6-1
Summary
The rat anti-mouse IL-2 monoclonal antibody (clone S4B6-1) is of the IgG2a subtype and neutralizes both natural and recombinant mouse IL-2 in vivo (Chaudhri G. et al. 2004). Zurawski S. et al. 1986 used the S4B6-1 antibody in Western blot analysis. Their analysis showed that the determinant recognized by S4B6-1 requires the N-terminal region of mouse IL 2 and there was no cross reaction with human IL-2. The S4B6-1 antibody is also applicable in immunohistochemistry on frozen tissues, intracellular staining, FACS analysis and immunoprecipitation (Chaudhri G. et al. 2004, Assenmacher M. et al. 1998 and Mosmann T. et al. 1990).

References list

  • Sequential production of IL-2, IFN-gamma and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes.
    Assenmacher, M, et al. Eur. J. Immunol. 1998 May;28: 1534-43
  • Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox.
    Chaudhri, Geeta, et al. Proc. Natl. Acad. Sci. U.S.A. 2004 Jun 15;101: 9057-62
  • Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.
    Cherwinski, H M, et al. J. Exp. Med. 1987 Nov 01;166: 1229-44
  • A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state.
    Grohmann, U, et al. J. Immunol. 1997 Apr 15;158: 3593-602
  • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
    Mosmann, T R, et al. J. Immunol. 1986 Apr 01;136: 2348-57
  • Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay.
    Mosmann, T R, et al. J. Immunol. 1990 Nov 01;145: 2938-45
  • Induction of IgG2a class switching in B cells by IL-27.
    Yoshimoto, Takayuki, et al. J. Immunol. 2004 Aug 15;173: 2479-85
  • Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity.
    Zurawski, S M, et al. J. Immunol. 1986 Nov 15;137: 3354-60
品牌介绍
U-Cytech位于荷兰,是全球著名的ELISPOT试剂盒生产商。生产各种人,大鼠,小鼠,猴,猩猩等ELISPOT试剂盒。产品丰富全面,质量一流。U-CyTech公司的透明ELISPOT培养板。该透明ELISPOT培养板的检测结果可以很方便的在倒置显微镜(普通的细胞室所具有的设备)下观察计数、或者采用酶联斑点自动图像分析仪分析。同时承载实验的培养板坚固耐用,容易清洗,不存在被加样枪头损坏的危险,使整个实验操作更为方便轻松。U-CyTech公司ELISPOT系统采用独特的黑色酶底物系统,显色系统非常灵敏并且稳定性更强,结果的保存期在6个月以上。U-CyTech公司提供的透明ELISPOT培养板预先进行了无菌处理。因此在包装未破损的情况下不需进行消毒处理。不过在细胞培养过程中还是应该注意无菌操作。红色或者蓝色斑点PVDF膜板经过干燥后可保存六个月。黑色斑点透明板干燥后可保存延长至两年。